Locally advanced pancreatic cancer
Conditions
Interventions
Concurrent CRT group
Patients will undergo chemotherapy with 100mg/m2 nab-PTX and 800 mg/m2 gemcitabine for 8 weeks. Concurrent radiotherapy will be also performed. After chemoradiotherapy, patients w
Sponsors
Takami Hideki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Locally advanced pancreatic cancer 2.Age 20<= and <=79 3.Performance status 0-1
Exclusion criteria
Exclusion criteria: 1.distant metastasis 2.severe drug allergy 3.viable multiple primary cancer 4.gastrointestinal invasion 5.apparent infectious status 6.history of abdominal radiotherapy 7.pregnant or breastfeeding female
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2-year survival rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurrence free survival, overall survival, pathological tumor reduction according to Evans grade, Tumor response defined by RECIST, rate of completion of preoperative therapy, rate of adverse effect, surgical morbidity, early tumor shrinkage, time to treatment failure | — |
Contacts
Public ContactHideki Takami
Nagoya University Graduate School of Medicine
Outcome results
None listed