Mild cognitive impairment Mild cognitive impairment
Conditions
Interventions
Take tablets containing b-lactoline or placebo once a day for 24 weeks
Cognitive function
Sponsors
Muto Shigeki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Age: Men and women 50 years or older when consent is obtained 2) MMSE-J score at pre-examination: Those with a score of 24 to 28 3) CDR (memory and orientation) at pre-examination: Those with a score of 0.5 4) Those who, after receiving a sufficient explanation before participating in this research, have a sufficient understanding and have obtained the informed consent of the research subject.
Exclusion criteria
Exclusion criteria: 1) Those who are currently undergoing treatment or follow-up for diseases (Epilepsy, stroke, dementia,Parkinson's disease, etc.) of the cranial nervous system 2) GDS score at pre-examination: Those with a score of 10 or more 3) Those who may have allergies to the raw material (milk) of research food 4) Those who is pregnant or going to be pregnant (female) 5) Those who cannot take MRI, such as pacemakers,body metal such as brain clips and bolts, tattoos (including tattoos and permanent makeup), etc. 6) Those who have difficulty distinguishing colors 7) Those who have participated in other clinical trials within 1 month before the pre-examination or who plan to participate in other clinical studies during this research period 8) Those who regularly drink more than properdrinking (about 20 g of alcohol per day: about 500mL of beer, about 180 mL of wine, about 180 mL ofsake, about 60 mL of whiskey double) 9) Those who have smoking habits 10) Those who continuously take supplements containing high amounts of protein (high protein supplements) for the purpose of strengthening muscle once a week or more 11) Those who have difficulty in taking research food (8 mm diameter tablets, 5 tablets per dose) 12) Those who are judged to be inappropriate by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function assessments (MMSE-J, MoCA-J) | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive function assessments, mental funciton assessments, QOL assessments | — |
Contacts
Public ContactTakayuk Ikeda
Seirei Medical Checkup Center
Outcome results
None listed