Food allergy (milk) Food allergy, milk allergy, anaphylaxis
Conditions
Interventions
Patients with milk allergy are randomized to receive A: hydrolyzed casein-containing hydrophilic gel patch or B: placebo hydrophilic gel patch on the skin 24 hours a day for 24 weeks. If the oral food
D003888
Sponsors
Takase Takafumi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.IgE-mediated milk allergy 2.Immediate allergic symptoms are induced in oral milk challenge by cumulative dose of milk at 3 ml or less 3.Written informed consent by a guardian and informed ascent by a participant(child)
Exclusion criteria
Exclusion criteria: Uncontrolled atopic dermatitis/bronchial asthma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients pass oral food challenge of cumulative amount of milk at 3 ml after epicutaneous immunotherapy | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency of occurrence of adverse events Changes in milk, casein, alpha lactalbumin, beta lactoglobulin specific IgE antibodies, and casein specific IgG4 antibodies Change in the diameter of the wheal in the Prick test Change in threshold values before and after the study treatment Proportion of participants who pass oral food challenge to 3ml of milk at 48 weeks | — |
Contacts
Public ContactTakafumi Takase
National Hospital Organization Mie National Hospital
Outcome results
None listed