Colorectal cancer
Conditions
Interventions
Preoperative ICG local injection.
Sponsors
Takemasa Ichiro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Age at the time of obtaining consent is 20 years or older. 2)Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0-2. 3)Primary colorectal cancer 4)Histological confirmation of colorectal cancer (adenocarcinoma). 5) A radical operation is planned. 6) Informed consent has been obtained.
Exclusion criteria
Exclusion criteria: 1)A case in which lower endoscope is difficult before surgery. 2)A case with indocyanine green hypersensitivity 3)A case with iodine hypersensitivity 4)Pregnant women, possibly pregnant women, wishing to become pregnant, and nursing mothers. Men with no intention to practice birth control. 5)Inadequate physical condition, as diagnosed by primary physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metastatic positive rate of ICG fluorescent lymph nodes and metastatic positive rate of ICG non-fluorescent lymph nodes in regional and not regional lymph nodes. | — |
Secondary
| Measure | Time frame |
|---|---|
| 3-year recurrence free survival 3-year overall survival Safety and short-term results (perioperative complications, postoperative hospital stay) Identification rate of tumor localization by ICG marking. Number of isolated lymph nodes. Number of ICG fluorescent lymph nodes. Number of metastatic lymph nodes. OSNA-positive rate. | — |
Contacts
Public ContactHidekazu Takahashi
Osaka International Medical & Science Center Osaka Keisatsu Hospital
Outcome results
None listed