The study for the hepatoprotective effect of steroid administration before hepatectomy in major hepatectomy with extrahepatic bile duct resection

The study for the hepatoprotective effect of steroid administration before hepatectomy in major hepatectomy with extrahepatic bile duct resection - The hepatoprotective effect of steroid administration before hepatectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs041180181

Enrollment

Registered

2019-03-29

Start date

2017-05-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

The steroids group received 500 mg hydrocortisone immediately before hepatic-pedicle clamping, followed by 300 mg hydrocortisone on postoperative day (POD) 1, 200 mg on POD 2, and 100 mg on POD 3.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)less than 20 years old 2)Patients who undergo major hepatectomy with bile duct resection 3)Patient who agree to participate in the study

Exclusion criteria

Exclusion criteria: 1)Patient who disagree to participate in the study] 2)Patient who does not appropriate to use steroid.

Design outcomes

Primary

Measure	Time frame
Liver failure	—

Secondary

Measure	Time frame
Maximum value of T-Bil and PT-INR	—

Contacts

Public ContactShunsuke Onoe

Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine

sonoe@med.nagoya-u.ac.jp+81-527442222

Outcome results