Health Condition
Conditions
Interventions
Improvement of nutritional condition in the patients with inoperable pancreatic cancer
Sponsors
Honda Takashi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients diagnosed as unresectable pancreatic cancer
Exclusion criteria
Exclusion criteria: 1.Women with pregnancy or possible pregnancy 2.Patients with severe renal failure and heart failure 3.Patient who is considered to be inappropriate for entry into the trial by the investigator 4.Patients with substantial alcohol consumption(20g/day for women or >30g/day for men 5.Patient who is poor in ingestion 6.Patient with other pancreas disease or other cancer 7.Patient who receive other treatments such as chemotherapy,radiotherapy and operation 8.Patients who take nonabsorbable antibiotics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of nutritional condition in the patients with inoperable pancreatic cancer | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Changes of Performance status(KPS) 2.Changes of The European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire(EURTC-QLQ-C30) 3.Changes of total energy expenditure(TEE) 4.Changes of short-chain fatty acid(Butyric acid,Acetic acid,Prorionic acid etc.) 5.Changes of Rapid turnover protein 6.Correlation of gut microbiota and therapeutic effect 7.Metabolome,bile acid and protein analysis of metabolite in feces 8.Correlation between expiratory noble gases,gut microbiota and pancreatic cancer 9.Successful execution rate of Chemotherapy 10.Frequency and degree of side effect 11.Prognosis of inoperable pancreatic cancer | — |
Contacts
Public ContactYoshiyuki Minami
Nagoya University Hospital
Outcome results
None listed