bipolar disorder bipolar disorder
Conditions
Interventions
taking lacosamide
D000078334
lacosamide
Sponsors
Kishi Taro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The clinical trial was described in detail to the subjects, and written informed consent was obtained from all participants and their guardians. 2. patients age: 20 > years olds and < 70 years old 3. Patients met at least 2 the following inclusion criteria -Patients did not improve their symptoms using at least one mood stabilizer with adequate dose for 4 weeks or more than 4 weeks. -Patients did not improve their symptoms using at least one second generation antipsychotic with adequate dose for 4 weeks or more than 4 weeks. -Patients did not improve their symptoms using combination therapy of mood stabilizer with second generation antipsychotic with adequate dose for 4 weeks or more than 4 weeks.
Exclusion criteria
Exclusion criteria: 1. patients receiving electroconvulsive therapy within 6 months prior to the study enrollment. 2. no pregnancy, no lactation. 3. no severe physical illness. 4. no neurological disease. 5. patients have suicidal ideation. 6. patients judged that researchers are inappropriate to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Global Impression-Severity | — |
Secondary
| Measure | Time frame |
|---|---|
| Young Mania Rating Scale, Hamilton Rating Scale for Depression, discontinuation rate, incidence of individual adverse events | — |
Contacts
Public ContactTaro Kishi
Fujita Health University Hospital
Outcome results
None listed