Maxillary and maxillary single tooth defects with indications for extraction
Conditions
Interventions
Two types of bone graft materials were randomly selected for ridge preservation.
Sponsors
Munakata Motohiro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who meet all of the following criteria are eligible. 1) Patients who are between 40 and 80 years old. 2) Patients with missing single tooth (premolar or bicuspid) in the upper and lower jaws who are seeking implant treatment after tooth extraction at the Implant Dentistry Department of Showa University Dental Hospital. 3) Patients who have given written consent to participate in this study.
Exclusion criteria
Exclusion criteria: Persons who violate any of the following will not be included in this study. 1) Smoking (2) Patients with osteoporosis, severe diabetes, rheumatoid arthritis, bone metabolism disease such as taking steroids or bisphosphonates (BP drugs), or taking drugs that interfere with bone metabolism (3) Patients with alcohol or drug dependence or psychiatric disorders (4) Patients who are undergoing or have undergone radiotherapy (5) Patients with cardiac disease, hematological disease, or collagen disease (6) Patients with renal failure or on dialysis (7) Pregnant, lactating, or possibly pregnant 8) Patients with a history of hypersensitivity or allergy to bone graft materials or membranes 9) Patients with large lesions, fistulas or acute symptoms (swelling and drainage of pus) of the tooth to be extracted 10) Patients who are deemed ineligible for participation in the study by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Radiological (CBCT) evaluation of horizontal and vertical bone volume changes (mm) with two types of bone grafting materials (Cytrans Granule and Bio-Oss). The horizontal bone width diameter and vertical bone height diameter (mm) of the alveolar bone were measured using the Materialise Mimics Innovation Suite (Materialise, Belgium), a medical image analysis software, from X-ray CT image data taken immediately after ARP and 6 months after ARP. The amount of change and the rate of change are calculated. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Calculation of area (mm3) and rate of change (%) of the crest of the jaw before tooth extraction, immediately after ARP, 3 months later, and 6 months later, based on data obtained from optical impressions: morphological 2) Bone tissue was harvested with a 1.7mm dia. trephine bar at the time of implant placement, and the residual rate of bone graft material and the rate of new bone formation were calculated using Villanueva-Goldner staining: pathological. 3) Changes in CT values of the bone graft area immediately after ARP and 6 months after ARP using X-ray CT image data: radiological 4) Measuring the implantation torque value when the implant body is placed: bone quality evaluation 5) The volume (mm3) of the alveolar bone of the bone graft was measured using the Materialise Mimics Innovation Suite (Materialise, Belgium), a medical image analysis software, from X-ray CT image data taken immediately after the ARP and 6 months after the ARP, and the volume change and the rate of change are calculated: radiological evaluation | — |
Countries
Japan, note
Contacts
Public ContactMotohiro Munakata
Showa medical university dental hospital
Outcome results
None listed