Keratoconus Keratoconus
Conditions
Interventions
Violet light, Glass
Sponsors
Hidenaga Kobashi
Tsubota Laboratory, Inc
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The principal investigator diagnosed keratoconus and satisfy one or more of the following items 1~5 within the 6 months immediately preceding the start of this study. 1.Corneal shape analysis Kmax increased by more than 0.5 D 2.Corneal shape analysis Posterior corneal best sphere fit (BSF) increased by more than 0.2 mm 3.Subjective astigmatism frequency increased by 0.5 D or more 4.Increased refractive index by 0.5 D or more (myopia) 5.Minimum corneal thickness reduced by more than 5 micrometre
Exclusion criteria
Exclusion criteria: Subjects who meet one or more of the following criteria will be excluded from the study: 1. Taking psoralen 2. History or suspicion of photosensitivity 3. History of epilepsy 4. History of allergy to fluorescein 5. When corneal transplantation may be required during the clinical research period 6 In addition, when the principal investigator deems the patient to be inappropriate as a subject of this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kmax | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Corneal shape analyzer (minimum corneal thickness, demarcation line) 2. Corrected visual acuity 3. Naked eye vision 4. Perceived spherical power 5. Subjective astigmatism frequency 6. Intraocular pressure 7. Corneal endothelial cell density 8. Corneal opacity and scarring 9. Slit lamp microscope and fundus examination 10. Retinal optical coherence tomography OCT 11. Adverse Events, Reports from Subjects or Delegates | — |
Contacts
Public ContactKondo Shinichiro
Tsubota Laboratory, Inc
Outcome results
None listed