Schizophrenia, Autism spectrum disorder Schizophrenia, Autism spectrum disorder, Transcranial Magnetic Stimulation, TMS, QPS
Conditions
Interventions
TMS treatment with QPS protocol
Sponsors
Kitahata Ryosuke
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients who meet the diagnostic criteria for schizophrenia/schizoaffective disorder or autism spectrum disorder in the DSM-5 2) Patients who have provided written informed consent to participate in this study 3) Male and female patients aged 20 to 65 at the time of obtaining written informed consent 4) Patients who have been attending the hospital regularly and have not changed their psychotropic drug for the past 3 months
Exclusion criteria
Exclusion criteria: 1) Patients with cerebral organic diseases (intermediate intracranial organic lesions or neurodegenerative diseases, etc.) 2) Patients with a history of seizures or epilepsy 3) Patients with a history of substance use disorders in the past 6 months 4) Patients who has received electroconvulsivetherapy in the past 6 months 5) Patients with serious or unstable physical illness 6) Patients being pregnant, breastfeeding, or hoping to become pregnant 7) Patients with alcohol allergy 8) Patients with contraindications to TMS or MRI procedures such as metal implants, pacemakers, claustrophobia, tattoos (including art makeup) larger than a single point (2 x 2 cm) on the head and neck 9) Patients whose head, neck, or body size is not suitable for MRI scanner 10) Patients who are judged to be inappropriate by the principal investigator or co-investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| For patients with schizophrenia Changes in PANSS score from baseline Changes in BNSS score from baseline For patients with autistic spectrum disorder: Changes in RBS-R score from baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events associated with TMS treatment by QPS protocol Changes in the following items from baseline For patients with schizophrenia CDSS, RBANS, LNST, SNST, TMT, EXI25 For patients with autistic spectrum disorder VABS2, SP | — |
Contacts
Public ContactShinichiro Nakajima
Shinjuku Yoyogi Mental Lab clinic
Outcome results
None listed