None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Persons who are 20 to 39 or below at the time of consent 2) Healthy male
Exclusion criteria
Exclusion criteria: 1) Patients with cochlear implants, cardiac pacemakers, or implanted VNS 2) Those with certain risks associated with MRI imaging (tattoos, art makeup, claustrophobia, etc.) 3) Those with injuries to the auricular region 4) Those who have undergone a myeloscopic shunt procedure 5) Patients with a diagnosis of glaucoma 6) Persons who smoke 7) Those requiring regular medication 8) Those who have consumed caffeinated beverages (coffee, black tea, green tea, energy drinks, etc.) on or after the day before the test 9) Other persons deemed inappropriate by the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change ratio of heart rate | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Change ratio of heart rate variability (HRV) 2. Change ratio of pupil diameter 3. Brain MRI image change 4. Heart rate counting task (HCT) 5. Multidimensional Assessment of Interoceptive Awareness (MAIA) Japanese version 6. STAI State-Trait Anxiety Inventory Japanese version 7. Japanese version of the SSS-8 | — |
Contacts
National Center of Neurology and Psychiatry