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Exploration of evaluation indices for taVNS

Exploration of objective evaluation indices for transcutaneous auricular vagus nerve stimulation in healthy adults.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs032220332
Enrollment
10
Registered
2022-09-13
Start date
2022-10-19
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

transcutaneous auricular Vagus Nerve Stimulation
taVNS

Sponsors

SEKIGUCHI Atsushi
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1) Persons who are 20 to 39 or below at the time of consent 2) Healthy male

Exclusion criteria

Exclusion criteria: 1) Patients with cochlear implants, cardiac pacemakers, or implanted VNS 2) Those with certain risks associated with MRI imaging (tattoos, art makeup, claustrophobia, etc.) 3) Those with injuries to the auricular region 4) Those who have undergone a myeloscopic shunt procedure 5) Patients with a diagnosis of glaucoma 6) Persons who smoke 7) Those requiring regular medication 8) Those who have consumed caffeinated beverages (coffee, black tea, green tea, energy drinks, etc.) on or after the day before the test 9) Other persons deemed inappropriate by the principal investigator

Design outcomes

Primary

MeasureTime frame
Change ratio of heart rate

Secondary

MeasureTime frame
1. Change ratio of heart rate variability (HRV) 2. Change ratio of pupil diameter 3. Brain MRI image change 4. Heart rate counting task (HCT) 5. Multidimensional Assessment of Interoceptive Awareness (MAIA) Japanese version 6. STAI State-Trait Anxiety Inventory Japanese version 7. Japanese version of the SSS-8

Contacts

Public ContactAtsushi SEKIGUCHI

National Center of Neurology and Psychiatry

asekiguchi@ncnp.go.jp+81-42-341-2711

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026