Efficacy of rTMS upper limb paralysis after cervical SCI

Efficacy of Rehabilitation with Repetitive Transcranial Magnetic Stimulation for Upper Limb Paralysis after Cervical Spinal Cord Injury - Efficacy of rTMS upper limb paralysis after cervical SCI

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs032220059

Enrollment

Registered

2022-05-11

Start date

2022-05-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical spinal cord injury

Interventions

repetitive Transcranial Magnetic Stimulation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Age: 20-80 (2) Under the agreement with written consent form (3) Diagnosed as cervical spinal cord injury by a physician (4) Inpatient at Chiba Rehabilitation Center (5) AIS C or D (6) 3 months after onset (7) The weekly upper extremity motor score ( the Prehension Performance item of GRASSP; The Graded Redefined Assessment of Strength, Sensibility and Prehension) is limited to a change within the standard error for two consecutive weeks

Exclusion criteria

Exclusion criteria: (1) Fit into following cases History of harmful sides effects due to magnetic or electrical stimulation, History of seizure or epilepsy, History of disease or injury of head, brain, peripheral nerves including brain surgery, Medical device implantation such as cardiac pacemaker, neurosurgical clips, battery or pumps, non-titanium metal implants in the head or the stimulus target area of trunk, Chronic severe migraine, Pregnant or suspicion of pregnancy (2) Unable to confirm that the implant is titanium (3) Inappropriate patient decided by a physician (4) Current participation in clinical trials for unapproved drug or clinical device (5) History of botulinum toxin therapy within 4 months (6) Over 17 points the Prehension Performance item of GRASSP (The Graded Redefined Assessment of Strength, Sensibility and Prehension)

Design outcomes

Primary

Measure	Time frame
Changes in measured value prime points for pre- and post-intervention measurements of the Graded Redefined Assessment of Strength, Sensibility and Prehension Version 2 (GRASPP); Prehension Performance item	—

Secondary

Measure	Time frame
GRASPP's Preintervention Performance item changes in measured value prime points from pre-intervention and post-intervention measurements at 1 month after the intervention, Total score of GRASSP, Subtest scores other than Prehension Performance item of GRASSP, American spinal injury association upper extremity motor score, Spinal Cord Independence Measure, Magnetic resonance imaging, Motor evoked potential elicited by transcranial magnetic stimulation, Safety Assessment	—

Measure

Time frame

GRASPP's Preintervention Performance item changes in measured value prime points from pre-intervention and post-intervention measurements at 1 month after the intervention, Total score of GRASSP, Subtest scores other than Prehension Performance item of GRASSP, American spinal injury association upper extremity motor score, Spinal Cord Independence Measure, Magnetic resonance imaging, Motor evoked potential elicited by transcranial magnetic stimulation, Safety Assessment

—

Contacts

Public ContactTakashi Murayama

Chiba Rehabilitation Center

takashi.murayama@chiba-reha.jp+81-43-291-1831

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026