Healthy adult Not applicable
Conditions
Interventions
1. After the subject is anesthetized with eye drops, a soft eyelid fixator is applied and the eyelids are opened.
2. The eyepiece is contacted and focused by the human aqueous Raman spectroscopy to ob
Sponsors
Kurihara Toshihide
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -Healthy adult(between 20 and 65 years of age) -Person with written informed consent personally
Exclusion criteria
Exclusion criteria: (1) The person who has diseases in eyeball or eyelid (2) The person who underwent ophthalmic surgery within 6 months (3) The person who received refractive surgery previously (4) The person that needs to consent by representative for participation to the study (5) The person who lacks in the ability of consent or is spoiled arbitrary property of consent for participation to the study (6) Treated with drugs which may affect cornea such as anti-cancer drugs, amiodarone, isotretinoin, etc. (7) Pregnant or breast-feeding woman (8) With a history of eye drop anesthetic hypersensitivity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the safety of a Raman spectroscopy system with aqueous humor for human subjects. | — |
Secondary
| Measure | Time frame |
|---|---|
| -To detect a significant and strong Raman peak in the Raman spectroscopy with human aqueous humor -To clarify target materials, identification of issues for Raman spectroscope with aqueous humor in vivo and extraction of factors to obtain favorable Raman spectroscopy | — |
Contacts
Public ContactAri Shinojima
Keio University School of Medicine (Keio University Hospital)
Outcome results
None listed