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Evaluation of the healing response of Coroflex ISAR Neo DES (polymer free DES) versus XIENCE (durable polymer DES) in patients with acute coronary syndrome: A Randomized Optical Coherence Tomography study

Evaluation of the healing response of Coroflex ISAR Neo DES (polymer free DES) versus XIENCE (durable polymer DES) in patients with acute coronary syndrome: A Randomized Optical Coherence Tomography study - HR-ACS2 study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs032210464
Enrollment
104
Registered
2021-12-02
Start date
2022-01-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Coronary Syndrome ACS, DES, OCT

Interventions

OCT observation in deployed stent at the end of emergency or urgent PCI.

Sponsors

Okazaki Shinya
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who diagnosed ACS and undergone emergency or urgent CAG, and including 1. and 2. 1. Age more than 20 2. Obtained informed consent from patients or their represent

Exclusion criteria

Exclusion criteria: 1. Age<20 2. patients who were planned to undergo CABG surgery 3. patients who cannot take antiplatelet drugs 4. patients who cannot be employed DES 5. patients who are taking chemotherapy or expected 6. patients who need to undergo invasive operation in 6 months 7. cardiac shock or acute decompensated heart failure 8. hemodialysis or Cr more than 2.0mg/dl 9. pregnancy or suspected, and breast feeding 10. others who decided unadequate

Design outcomes

Primary

MeasureTime frame
Covered struts ratio observed by OCT after 6 months

Secondary

MeasureTime frame
Covered struts ratio observed by OCT after 1 months

Contacts

Public ContactHidetoshi Yasuda

Juntendo University Hospital

hd-yasuda@juntendo.ac.jp+81-3-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026