magnetic stimulation of skeletal and respitatory muscle for COVID-19

A study of maintenance of skeletal and respitatory muscle quantity by magnetic stimulation for COVID-19

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs032210201

Enrollment

Registered

2021-07-16

Start date

2021-07-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COVID-19

Interventions

We perform the magnetic stimulation to bilateral phrenic nerve and light quadriceps muscle using Pathleader.

COVID-19

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Part 1: 1) Healthy persons who do not have cardiopulmonary diseases 2) Men or women more than 19years old at informed consent 3) Persons from whom informed consent were obtained with sufficient understanding and by their free will after detailed explanation on participating this study Part 2: 1) Patients with severe COVID-19 in ICU of Tokyo Medical and Dental University 2) men or women who are more than 19 years at informed consent 3) Patients from whose proxies informed consent were obtained with sufficient understanding and by their free will after detailed explanation on participating this study ( from patients if possible)

Exclusion criteria

Exclusion criteria: 1) pace-maker user 2) The patient who is judged to be inappropriate as a study subject by a study responsibility doctor and a study allotment doctor (the following study responsibility doctors)

Design outcomes

Primary

Measure	Time frame
Part I: Healthy persons (Outcomes assessment) The changes of the following outcomes between before with 1, 2 and 3weeks after stimulation 1. The muscle thickness and the muscle mass area at the center of bilateral quadriceps by ultrasonography 2. The thickness of diaphragm by ultrasonography 3. The circumference of the thighs at 5, 10, 15, 20 cm beyond the upper edge of the patella Part 2: Patients with severe COVID-19 (Outcomes assessment) The changes of the following outcomes between before with every week to the end of sedation and the start of active movements 1. The muscle thickness and the muscle mass area at the center of bilateral quadriceps by ultrasonography 2. The thickness of diaphragm by ultrasonography 3. The circumference of the thighs at 5, 10, 15, 20 cm beyond the upper edge of the patella	—

Measure

Time frame

Part I: Healthy persons (Outcomes assessment) The changes of the following outcomes between before with 1, 2 and 3weeks after stimulation 1. The muscle thickness and the muscle mass area at the center of bilateral quadriceps by ultrasonography 2. The thickness of diaphragm by ultrasonography 3. The circumference of the thighs at 5, 10, 15, 20 cm beyond the upper edge of the patella Part 2: Patients with severe COVID-19 (Outcomes assessment) The changes of the following outcomes between before with every week to the end of sedation and the start of active movements 1. The muscle thickness and the muscle mass area at the center of bilateral quadriceps by ultrasonography 2. The thickness of diaphragm by ultrasonography 3. The circumference of the thighs at 5, 10, 15, 20 cm beyond the upper edge of the patella

—

Contacts

Public ContactTomoko Sakai

Tokyo Medical and Dental University

t_sakai.orth@tmd.ac.jp+81-3-5803-5648

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026