HN LET

Feasibility study of dose-average LET optimized carbon-ion radiotherapy for head and neck cancers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs032210020

Enrollment

Registered

2021-04-07

Start date

2021-10-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer Head and neck cancer

Interventions

Carbon-ion radiotherapy is performed using medical heavy particle accelerator (HIMAC) installed at National Institutes for Quantum Science and Technology. The irradiation volume includes the tumor ide

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Pathological proven head and neck cancer except oral and pharyngolaryngeal squamous cell carcinoma. 2. No extensive neck lymph node metastases, no distant metastases. 3. Performance status 0 to 1 4. No other life-threatening illness 5. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Severe complication 2. Active double primary 3. Prevvious irradiation at tumor site 4. Severe infection at tumor site 5. Medically, psychologically or other reason who are not suitable for candidate

Design outcomes

Primary

Measure	Time frame
Acute reactions of normal tissues	—

Secondary

Measure	Time frame
Preliminary local effect (non-PD rate)	—

Contacts

Public ContactMasashi Koto

QST Hospital, National Institutes for Quantum Science and Technology

koto.masashi@qst.go.jp+81-43-206-3306

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026