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Study on brain function disease treatment with iterative transcranial magnetism stimulation method applicationusing the cognitive function improvement

Study on brain function disease treatment with iterative transcranial magnetism stimulation method applicationusing the cognitive function improvement

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs032200028
Enrollment
150
Registered
2020-05-08
Start date
2020-05-08
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia,Chronic insomnia,Painful disorder,Developmental disorders,strong catastrophic thinking

Interventions

One rTMS will be conducted once a day, and 1-5 days a week. After 1-20 sessions (in 1-4 weeks), symptoms and conditions of participants will be evaluated.

Sponsors

Takahashi Hidehiko
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with schizophrenia (i)Participants need to be outpatients of department of psychiatry, Institute of Science Tokyo Hospital. (ii) Participants need to be diagnosed as schizophrenia and other psychotic disorders, or schizophrenia spectrum in DSM-IV-TR or DSM-V. (iii)Participants don't have mental disabilities. (iv)Age at the time of enrolment need to be over 20 years old and under 50 years old. (v)Participants need to give informed consent by themselves on paper. Developmentally disabled patient (i)Participants need to be outpatients of department of psychiatry, Institute of Science Tokyo Hospital. (ii) Participants need to be diagnosed as autistic spectrum disorder or attention lack in DSM-IV-TR or DSM-V. (iii)Participants don't have mental disabilities. (iv)Age at the time of enrolment need to be over 20 years old and under 50 years old. (v)Participants need to give informed consent by themselves on paper. Chronic insomnia (sleep state misconception) (i)Participants need to be outpatients of department of psychiatry, Institute of Science Tokyo Hospital. (ii) Participants need to be diagnosed as sleeplessness disorder in DSM-IV-TR or DSM-V. (iii)Participants don't have mental disabilities. (iv)Age at the time of enrolment need to be over 20 years old and under 50 years old. (v)Participants need to give informed consent by themselves on paper. Painful disorder (i)Participants need to be outpatients of department of psychiatry, Institute of Science Tokyo Hospital. (ii)Participants need to be diagnosed as painful disroder in DSM-IV-TR or DSM-V. (iii)Participants don't have mental disabilities. (iv)Age at the time of enrolment need to be over 20 years old and under 50 years old. (v)Participants need to give informed consent by themselves on paper. Patients with strong catastrophic thinking about pain (i)Participants need to be outpatients of department of psychiatry, Institute of Science Tokyo Hospital. (ii)There is pain by some kind of physical diseases and gets a score 35 points or more with the catastrophic thought standard of the pain. (iii)Participants don't have mental disabilities. (iv)Age at the time of enrolment need to be over 20 years old and under 50 years old. (v)Participants need to give informed consent by themselves on paper.

Exclusion criteria

Exclusion criteria: 1. User of cardiac pacemaker 2. User of brain vascular clip 3. User of electric stimulator for neurons 4. User of implanted pump in body 5. One having remaining metallic piece in one's body 6. One having tattoo 7. One having treatment with electroconvulsive therapy 8. One having comorbid disorder below, Substance related disorders Severe heart disease 9. One having past history below, Substance related disorders Brain injury with loss of consciousness 10. Female having possibility of pregnancy. Female having breast-feeding. Male of Female not using birth control during research 11. One having been judged as inappropriate for research by researcher and doctors.

Design outcomes

Primary

MeasureTime frame
Positive And Negative Symptoms Scale (PANSS) Adult ADHD Self-Report Scale Pittsburgh Sleep Questionnaire Visual analog scale for pain pain catastrophizing scale(PCS)

Secondary

MeasureTime frame
Word Fluency test Color Stroop Test (CST) Wisconsin Card Sorting Test (WCST) Trail Making Test (TMT) EEG-related event-related potentials

Contacts

Public ContactHidehiko Takahashi

Institute of Science Tokyo Hospital

hidepsyc@tmd.ac.jp+81-3-3813-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026