Keratoconus Keratoconus
Conditions
Interventions
Violet light, Glass
Sponsors
Itoi Motozumi
Tsubota Laboratory, Inc.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Eyes with progressive keratoconus over the preceding 6 months as the following criteria. 1. an increase of at least 0.5 D in the Kmax 2. an increase of at least 0.2 mm in the corneal best sphere fit (BSF) 3. an increase of at least 0.5 D in the manifest cylindrical refraction 4. an increase of at least 0.5 D in the manifest refractive spherical equivalent 5. an decrease of at least 5 micro m in the thinnest corneal thickness
Exclusion criteria
Exclusion criteria: 1.Present medication of Psoralen 2.History of photodermatosis 3.History of epilepsy 4.History of fluorescein induced allergy 5.Cases with possibly undergoing keratoplasty during the observation period 6.Cases considered as inappropriate by physicians
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kmax | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Corneal Tomography (Thinnest corneal thickness, anterior and posterior parameters) 2.Best corrected visual acuity 3.Uncorrected visual acuity 4.Manifest refractive spherical equivalent 5.Manifest cylinder refraction 6.Intraocular pressure 7.Corneal endothelial cell density 8.Corneal haze, demarcation line 9.Slit lump examination 10.Optical coherence tomography 11.Dermal disorder 12.Adverse events and patient's report | — |
Contacts
Public ContactHidenaga Kobashi
Tsubota Laboratory, Inc.
Outcome results
None listed