epilepsy epilepsy
Conditions
Interventions
Direct recording of brain activity by an intracranial hybrid electrode composed of electrocorticographical macroelectrodes and microelectrodes
Sponsors
Shimada Seijiro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients with epilepsy who meet any of the followings (1 drug resistance, 2 drug use difficulty due to side effects, 3 high expectancy of seizure freedom by surgery, which leads to significant benefit on social life) 2) Patients who undergo intracranial electrode placement for the purpose of epileptic focus localization and functional brain mapping 3) Patients who are 16 to 60 years old at the time of consent acquisition 4) Patients who signed the consent form by the patient's own free will after sufficient explanation and understanding on participating in this study 5) Gender does not matter
Exclusion criteria
Exclusion criteria: 1) Patients with intellectual impairment and higher brain dysfunction (full scale IQ <60 by WAIS or WISC) 2) Patients whose participation in this study is judged as inappropriate by the principal investigator/subinvestigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decoding accuracy of brain activity recorded by hybrid electrodes | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Evaluation of temporal improvement of decoding accuracy by feedback of brain activity measured using hybrid electrodes (2) Evaluation of an association between brain activity measured using a hybrid electrode and electroencephalographical indeces of epileptogenicity (ictal or interictal) (3) Incidence of adverse events or related diseases | — |
Contacts
Public ContactSeijiro Shimada
The University of Tokyo Hospital
Outcome results
None listed