Investigational study of anti-adhetion effect of carboxymethyl cellulose sheet containing hyaluronic acid (Seprafilm) for pediatric cardiac surgery.

Investigational study of anti-adhetion effect of carboxymethyl cellulose sheet containing hyaluronic acid (Seprafilm) for pediatric cardiac surgery. - ISACS

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs032180393

Enrollment

Registered

2019-03-20

Start date

2019-11-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital heart disease congenital heart disease

Interventions

Put the carboxymethyl cellulose sheet containing hyaluronic acid (Seprafilm) to pericardiac lesion (heart, aorta, pulmonary artery, SVC, IVC) and infrasternal space before closing the chest.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patient who underwent (1) cardiac palliative procedure via median sternotomy or (2) Glenn procedure or other cardiac palliative procedure in advance of Fontan procedure.

Exclusion criteria

Exclusion criteria: 1. preoperative hemodynamic state is fragile 2. MRSA positive 3. difficult to sternal closure

Design outcomes

Primary

Measure	Time frame
postoperative degree of adhesion	—

Secondary

Measure	Time frame
necessary time for dissecting the adhesion at the next operation	—

Contacts

Public ContactYukihiro Yoshimura

Tokyo Metropolitan Children's Medical Center

yukihiro_yoshimura@tmhp.jp+81-42-300-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026