Skin defect Skin defect, skin graft
Conditions
Interventions
Skin grafts are fixed by negative pressure closure with RENASYS (Smith & Nephew).
Skin graft, negative pressure closure
Sponsors
Nakamura Yoshiyuki
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with defects in the trunk and extremities of >10 cm in size, or with muscle exposure.
Exclusion criteria
Exclusion criteria: Defects with contraindication for negative pressure closure (defects with exposure of main vessels, organs or nerves. Defects with fissures connected with organs or untested fissures. Defects with liquorrhea or digestive system fistula, which are suspected to become severer by negative pressure closure. Defects with necrosis, osteomyelitis with osteonecrosis or apparent malignant tumor.) Dialysis patients, diabetic patients (HbA1c>8%), patients with systemic steroid therapies (>prednisolone 20mg/ day). Defects of which the fixation by negative pressure closure is difficult because of hubby surface of surrounding tissues. Defect with bone exposure. Cases in which the devices are possible to be broken because of difficulty of keeping the patient at rest. A patient who shows more than 2 skin defects that fit the inclusion criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety | — |
Secondary
| Measure | Time frame |
|---|---|
| Graft survival 7 and 10 after surgery, time between starting the graft stabilization and the end of the operation, and time between surgery and hospital discharge | — |
Contacts
Public ContactYoshiyuki Nakamura
University of Tsukuba
Outcome results
None listed