Schizophrenia Schizophrenia
Conditions
Interventions
Transcranial direct current stimulation will be performed using a low-intensity tDCS (Model 1300A
Soterix Medical Inc., New York, USA) that delivers direct current through two 35 cm2 electrodes. The anode electrode will be placed over the left superior temporal sulcus, and the cathode will be plac
tDCS
Sponsors
Sumiyoshi Tomiki
Intramural Research Grant (30-1) for Neurological and Psychiatric Disorders of National Center of Neurology and Psychiatry (NCNP)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. patients diagnosed as Schizophrenia in DSM-5 2. patients aged between 20 and 70 3. patients who can understand the objective and content of the study and provide consent to participate in it. 4. patients whose SCSQ score is less than 34 points.
Exclusion criteria
Exclusion criteria: 1. patients with a present or past history of severe organic lesions and/or injury in the brain or dementia, or epilepsy. 2. patients with alcohol or substance use disorder that wass present within 12 months from the start of study 3. ECT or tDCS is clinically contraindicated. 4. patients who were treated with tDCS or other neuro-modulation within the past two months. 5. patients deemed inappropriate to participate by judgment of the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SCSQ(Social Cognition Screening Questionnaire) | — |
Secondary
| Measure | Time frame |
|---|---|
| False Belief Task, FEST (Facial Emotion Selection Test), AQ (Autism-Spectrum Quotient), UPSA-B (Brief UCSD Performance-based Skills Assessment), PANSS (Positive and Negative Syndrome Scale), JART25 (Japanese Adult Reading Test-25), BACS (The Brief Assessment of Cognition in Schizophrenia) | — |
Contacts
Public ContactYuji Yamada
National Center of Neurology and Psychiatry
Outcome results
None listed