Normal subjects
Conditions
Interventions
Positron emission tomography study using un-approved ligand [18F]FSW-100
Sponsors
Ishii Kenji
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: The following criteria must be met by all subjects. 1. Males who are between 20 and 60 years old at the time of obtaining consent 2. Those who have given written consent to participate in this study
Exclusion criteria
Exclusion criteria: Subjects who have any of the following present or past history of illness: 1. Past history of neuropsychiatric illness such as epilepsy, major depression, or schizophrenia 2. Smokers 3. Subjects who are judged to be unsuitable for head MRI examination 4. Subjects with past history of severe drug hypersensitivity 5. Subjects with past history of cardiovascular disease 6. Subjects who are currently suffering from chronic anemia and chronic renal failure. 7. Subjects who are judged by the primary investigator to be ineligible for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of safety, pharmacokinetics (metabolism, blood clearance, urinary excretion rate) and human radiation dosimetry associated with administration of [18F]FSW-100 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Optimization of data acquisition methods and scanning protocol 2.Establishment of quantification 3.Building appropriate methods for image evalua tion and analysis | — |
Contacts
Public ContactMami Yoshioka
Tokyo Metropolitan Institute for Geriatrics and Gerontology
Outcome results
None listed