Heart failure patients scheduled to undergo home-based cardiac rehabilitation heart failure
Conditions
Interventions
hochuekkito administered three times daily (2.5 g each, 7.5 g / day)
Sponsors
Amiya Eisuke
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients performing home-based cardiac rehabilitation 2) Patients with stage C heart failure staging in ACCF/AHA guidelines 3) Patients who can walk independently 4) Patients aged 18 or older 5) Male or female 6) Patients who can take study drug orally 7) Patients who are able to provide written consent
Exclusion criteria
Exclusion criteria: 1) Patients with biventricular pacemaker placement or after implantation of a ventricular assist device 2) Patients with a history of heart transplantation 3) Patients at risk of severe arrhythmia, including ventricular tachycardia 4) Patients with serum potassium levels less than 3.0 mEq/L within 12 weeks before enrollment 5) Patients with severe liver or renal disorder 6) Patients with malignant tumors 7) Patients with mental illness who cannot respond to questionnaire surveys 8) Patients who have a history of allergies or side effects (such as pseudo aldosteronism) in kampo (herbal medicine) 9) Patients with a history of serious drug allergy such as anaphylactic shock or a history of serious side effects 10) Patients taking prohibited drugs or study drugs within 2 weeks before consent 11) Pregnant or potentially pregnant patients 12) Lactating patient 13) Patients with symptoms such as eczema and dermatitis 14) Other patients who are judged inappropriate for participation in this study by the investigator or co-investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Walk distance of six-minute walk test | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Muscle strength (Grip strength) 2) Motivation (Apathy scale score) 3) Fatigue, Shortness of breath, Appetite (VAS) 4) QOL (EQ-5D-5L Japanese version) 5) Physical activity (Number of steps) 6) Nutrition (Body weight, Prealbumin) 7) Heart function (BNP) | — |
Contacts
Public ContactEisuke Amiya
The University of Tokyo Hospital
Outcome results
None listed