atrial fibrillation and atrial tachycardia arrhythmia
Conditions
Interventions
Catheter ablation with Vein of Marshall ethanol infusion
Sponsors
Fujiu Katsuhito
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: [Primary Enroll] 1. Diagnosed with atrial tachycardia or atrial fibrillation (paroxysmal or persistent) , including patients who have received catheter ablation 2. Scheduled to have a catheter ablation 3. Aged older than 18 years at the time of informed consent 4. Male or female 5. Able to attend all scheduled visits 6. Able and willing to give written informed consent with sufficient understanding after having received sufficient explanation [Secondary Enroll] Unable to be treated successfully with conventional catheter ablation: 1. Unable to perform linear ablation 2. Unable to complete pulmonary vein isolation due to electrical connection between pulmonary vein and Vein of Marshall 3. Arrhythmia originating from Vein of Marshall
Exclusion criteria
Exclusion criteria: [Primary Enroll] 1. With defect of Vein of Marshall 2. With ethanol allergy 3. With severe liver failure: e.g. total bilirubin of above 3.0 mg/dL and with uncontrolled ascites 4. With severe hemorrhagic diathesis, except for anticoagulant therapy 5. Taking drugs for alcoholism: disulfiram and cyanamide 6. Judged as ineligible by clinical investigators [Secondary Enroll] 1. With defect or stenosis of vein of Marshall 2. Judged as treated successfully with conventional catheter ablation procedure by clinical investigators 3. Judged as ineligible by clinical investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and rate of severe adverse events after chemical ablation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence and rate of adverse events after chemical ablation 2. Incidence and rate of adverse events related to ethanol injection procedure 3. Rate of successful procedure completion 4. Rate of maintenance of sinus rhythm at discharge | — |
Contacts
Public ContactTsukasa Oshima
The University of Tokyo Hospital
Outcome results
None listed