colorectal cancer
Conditions
Interventions
Off-label use of indocyanine green for detecting sentinel lymph nodes during surgery of colorectal cancer
indocyanine green
Sponsors
Ishihara Soichiro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) With a histological diagnosis of colorectal cancer (2) Scheduled to have any surgery for the colorectal cancer (3) With an ECOG performance status of 0 or 1 (4) Aged 18 years and above at the time of informed consent is taken (5) Male or female (6) Able and willing to give written informed consent with sufficient understanding after having received sufficient explanation
Exclusion criteria
Exclusion criteria: (1) With allergy to indocyanine green (2) With iodine allergy or with allergy to iodine contrast (3) With severe liver failure, renal failure, or cardiac disease (4) With bowel obstruction (5) With intraperitoneal infection (e.g. peritonitis or intraperitoneal abscesses) (6) Difficult colonoscopy (7) Having a history of severe drug allergy or severe side effects (8) Pregnant, unwilling to practice contraception during the study, or lactating female (9) Judged as ineligible by clinical investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of subjects with resection line changed from baseline due to ICG fluorescence | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) The lymph flow detected during surgery (2) The number of lymph nodes resected during surgery (3) Incidence of adverse events | — |
Contacts
Public ContactKoji Murono
The University of Tokyo Hospital
Outcome results
None listed