Patient undergoing craniotomy Cerebral aneurysm, Moyamoya disease, Intracranial tumor
Conditions
Interventions
Medication: Three packets of Saireito per day, divided into three doses, are administered orally before or between meals. The administration period is one week before and one week after surgery, for a
Sponsors
Ito Yoshiro
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients undergoing craniotomy with an anterior temporal craniotomy 2) Patients who are at least 18 years old and less than 75 years old 3) Patients who have been fully informed and understood about the study, and have given written informed consent
Exclusion criteria
Exclusion criteria: 1) Patients using steroids or interleukin inhibitors 2) Female who are pregnant or may become pregnant 3) Lactating female 4) Patients who have received any other study drug or investigational drug within 3 months prior 5) Other patients who are deemed inappropriate as subjects by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total number of analgesics used in 9-15 days (postoperative day 1-7) | — |
Secondary
| Measure | Time frame |
|---|---|
| Day 9 (postoperative day 1) (VAS, temporalis muscle swelling rate, WBC, CK, IL-6, IL-8, IL-10), Day 15 (postoperative day 7) (VAS, QoR40, pain level by Pain vision) | — |
Contacts
Public ContactYoshiro Ito
University of Tsukuba Hospital
Outcome results
None listed