Cystinosis Cystinosis
Conditions
Interventions
Administration of A0003 Eye Drops 0.55% 4 times day for 52 weeks
cysteamine eyedrops
Sponsors
Yamamoto Yuuka
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with cystinosis who meet the following criteria 1) Patients with presence of corneal cystine crystal deposits assessed during ophthalmic examination 2) Patients who have ability to or intend to comply with the 4 times daily instillation regimen 3) Patients who are judged by the principal investigator or sub-investigator to be appropriate for inclusion in the study. 4) Patients who have given written consent to participate in the research in person. 5) Patients who are at least 18 years of age at the time consent is obtained
Exclusion criteria
Exclusion criteria: 1) Patients who are obviously suffering from a serious acute disease 2) Patients with a history of hypersensitivity to the active ingredients or additives of the test drug 3) Pregnant or possibly pregnant or lactating women 4) Persons who are judged by the principal investigator to be inappropriate for inclusion in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Luminance waveform analysis (LWA) by using AS-OCT | — |
Secondary
| Measure | Time frame |
|---|---|
| Photophobia rated by investigators Photophobia rated by patients | — |
Contacts
Public ContactTadashi Okamura
Reserch Insitute, the National Center for GlobalHealth and Medicine
Outcome results
None listed