Heart disease (myocardial infarction or angina, post-open heart surgery, chronic heart failure) Heart disease (myocardial infarction or angina, post-open heart surgery, chronic heart failure)
Conditions
Interventions
Use 1.5 g of HMB-Ca tablets. The study period is 60 days from the start of cardiac rehabilitation. 52 patients were randomly divided into 2 groups, HMB-Ca group consuming 1.5 g of 6 tablets of HMB-C a
Sponsors
Hiroo Ichikawa
Ikeda Takashi
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients who newly started outpatient cardiac rehabilitation at Showa University Fujigaoka Rehabilitation Hospital 2) Patients with heart disease (myocardialinfarction or angina, post-open heart surgery, chronic heart failure) as the name of rehabilitation disease 3) Patients who voluntarily consented to the document after receiving an explanation using the patient's document when participating in this study. 4) Patients are 40 years of age or more.
Exclusion criteria
Exclusion criteria: 1) Patients with severe renal dysfunction (eGFR <30), dialysis patients 2) Patients who have difficulty in continuous exercise therapy for 20 minutes or more due to factors other than heart disease 3) Patients with depression / schizophrenia / dementia 4) Patients with dysphagia 5) Patients with untreated cardiovascular diseaseand limited exercise therapy 6) Patients with restricted energy and protein intake due to diabetes and renal dysfunction 7) Patients who had not been hospitalized for heart disease within 6 months and had undergone outpatient cardiac rehabilitation 8) Other patients who the principal investigator deems inappropriate as a subject
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quadriceps muscle strength | — |
Secondary
| Measure | Time frame |
|---|---|
| grip strength lower limb extension strength Skeletal muscle mass quadriceps muscle thickness Energy consumption (physical activity) Short Physical Performance Battery(SPPB) 10-m timed gait test SF-12v2 Japanese edition cardiopulmonart exercise testing(peakVO2,Peak-Load,AT) albumin total protein brain natriuretic peptide creatinine blood urea nitrogen estimated glomerular filtration rate cystatin C calcium creatine kinase CK-MB microRNA(miR-181a, miR-181b, miR-181c, miR-484) BDNF(Brain Derived Neurotrophic Factor) nutritional components in urine and dietary survey | — |
Contacts
Public ContactMiyazawa Ryo
Showa Medical University Fujigaoka Rehabilitation Hospital
Outcome results
None listed