Effect of Astragalus Root on CKD

Effect of Astragalus Root on improving renal function in chronic kidney disease: a prospective intervention study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs031210058

Enrollment

160

Registered

2021-04-27

Start date

2021-06-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease Chronic kidney disease

Interventions

Astragalus Root powder (0.07g/kg/day) given orally 2 times daily from 3 months to 15 months after registration

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Chronic kidney disease (CKD) 2) eGFR: 15-60mL/min/1.73m2 (stage3 or 4) 3) Age: = or >20 years old 4) Male and female 5) Outpatient of Kampo medicine clinic or general medicine clinic at Tokai university hospital, or clinic of Shonan hospital 6) No major changes in medication 7) Written informed consent

Exclusion criteria

Exclusion criteria: 1) Improper dosing 2) Allergies to Kampo medicine 3) Pregnant

Design outcomes

Primary

Measure	Time frame
slope of eGFR	—

Secondary

Measure	Time frame
1. eGFR 2. SCr 3. BUN 4. Protein-to-creatinine ratios (Up/Cr)	—

Contacts

Public ContactMasayuki Oki

Tokai University Hospital

okixx007@tokai.ac.jp+81-463-93-1121

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026