Healthy adult
Conditions
Interventions
26-week application of retinyl palmitate gel to one side of the face and placebo gel to the other side twice a day morning and evening
Sponsors
Miyata Akinobu
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Healthy adult female 2) Wrinkle grades between 3 and 5
Exclusion criteria
Exclusion criteria: 1) Subjects with skin lesions at the test site (atopic dermatitis, hives, inflammation, eczema, injury, acne spots, knots, speckles, or their traces) 2) Subjects with experience of cosmetology (botox injection, hyaluronic acid or collagen injection, photofacial, etc.) at the test site, or plan to receive it during the test period 3) Subjects with pregnant, breastfeeding, or plan to do so 4) Subjects who the principal investigator judges inadequate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| wrinkle area ratio, total wrinkle average depth, maximum wrinkle average depth, maximum wrinkle maximum depth | — |
Secondary
| Measure | Time frame |
|---|---|
| wrinkle grades | — |
Contacts
Public ContactTakeshi Kaneko
Japan Clinical Trial Association
Outcome results
None listed