chronic liver disease chronic liver disease , vitamin D
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with chronic liver disease 20 years old or older, under 85 years old Both hospitalization / outpatient Patients with serum 25 (OH) D3 concentration deficiency less than 20 ng / ml
Exclusion criteria
Exclusion criteria: Hepatic encephalopathy more than 3 Total bilirubin value >3 mg/dl Patien with decrease of the protein composition ability in the liver The patient allergic to milk The patient who is nursing and pregnant Patient with uncotrolled HCC or other malignant tumor Uncontrolled heart failure patient Uncontrolled hypertension or diabetes Patient with Chronic renal failure Patient of hypercalcemia Patient with hyperthyroidism Patient who already takes other vitamin D Patien who takes the drug that combination with the vitamin D preparation is contraindicated Patient with acute liver failure Patient who were judged unsuitable by test responsibility doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skeletal muscle mass, grip, Liver fibrosis | — |
Contacts
Nippon Medical Chiba Hokuso Hospital