Ascorbic acid treatment for childhood Charcot-Marie-Tooth disease 1A

Ascorbic acid treatment for childhood Charcot-Marie-Tooth disease 1A - Ascorbic acid for CMT1A

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs031190109

Enrollment

Registered

2019-10-03

Start date

2019-10-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Charcot-Marie-Tooth disease type 1A CMT1A

Interventions

ascorbic acid dayly intake

ascorbic acid

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Children under 18 years of age with confirmed PMP22 duplication in genetic testing. 2. Normal data in blood examination. 3. Normal data in urinary analysis. 4. Written informed consent from the patient, or parents in case of children.

Exclusion criteria

Exclusion criteria: 1. The patient has already taken daily vitamin treatment. 2. When the investigator or the investigator considers it inappropriate to conduct this study safely.

Design outcomes

Primary

Measure	Time frame
CMT score	—

Secondary

Measure	Time frame
Electrophysiological examination, Six minutes walking distance	—

Contacts

Public ContactTADASHI SHIOHAMA

Chiba University Hospital

asuha_hare@chiba-u.jp+81-43-226-2144

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026