The inhibitory effect of lidocaine hydrochloride salt on duodenal peristalsis during ERCP:a muiticenter, randomized, placebo-controlled trial.

The inhibitory effect of lidocaine hydrochloride salt on duodenal peristalsis during ERCP:a muiticenter, randomized, placebo-controlled trial. - Lidocaine trial(LT)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs031190059

Enrollment

Registered

2019-07-23

Start date

2019-10-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute cholangitis,Obstructive jaundice,Pancreatic cancer,IPMN

Interventions

Investigational product:To spray A(2% lidocaine hydrochloride 10ml+normal saline solution 10ml) for papilla Control drug:To spray B(PG water EJ 10ml+normal saline solution 10ml) for papilla

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.over the age of 65 under the age of 90 2.Adaptation of ERCP 3.Score of peristalsis 1-3 4.Written informed consent

Exclusion criteria

Exclusion criteria: 1.Acute pancreatitis 2.Allergy of Amide-type local anesthetic allergy 3.Altered upper GI anatomy 4.Pregnant,unwilling to practice contraception during the study, or lactating female 5.Heart stimulus conduction disorders 6.severe liver or kidney dysfunction 7.score of peristalsis:4,5 8.A patient who has judged to be inappropriate as a target by the judgement of the practitioner

Design outcomes

Primary

Measure	Time frame
Ceased peristalsis	—

Secondary

Measure	Time frame
Required time,Stop duration time,Adverese events	—

Contacts

Public ContactKunihiro Hosono

Yokohama City University Hospital

hiro1017@yokohama-cu.ac.jp+81-45-787-2800

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026