Skip to content

In vivo quantification of central phosphodiesterase 7

In vivo quantification of central phosphodiesterase 7 using [11C]MTP38

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs031190054
Enrollment
12
Registered
2019-07-12
Start date
2019-08-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition

Interventions

Injection of [11C]MTP38

Sponsors

Tagai Kenji
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Healthy male subjects

Exclusion criteria

Exclusion criteria: 1.Subjects who do not have ability to make informed consent. 2. Subjects with any psychiatric disorder or subjects with severe physical complication. 3. Subjects who currently smokes. 4. Subjects with any organic brain disorder. 5. Subjects with metallic medical device in the body. 6. Subjects with tattoo. 7. Subjects with severe claustrophobia. 8. Subjects with a history of allergy to heparin and local anesthetics. 9. Subjects who are taking an anticoagulant. 10. Subjects who has participated in other study in recent 6 months. 11. Subjects who has participated in blood donation in recent 12 weeks. 12. Subjects who is considered to be inappropriate to participate in the study.

Design outcomes

Primary

MeasureTime frame
Pharmacokinetics, and distribution volume or binding potentials of [11C]MTP38 in human brain

Secondary

MeasureTime frame
Association between distribution volume of [11C]MTP38 and MRI data

Contacts

Public ContactKenji Tagai

Institute for Quantum Medical Science, Quantum Medical Science Directorate, National Institutes for Quantum Science and Technology (QST)

tagai.kenji@qst.go.jp+81-43-206-3251

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026