Breast cancer
Conditions
Interventions
Start takig orally of letrozole (e.x. FEMARA 2.5mg, 1 to 2 tablet/day) on the assigned day, and stop taking FEMARA after the confirmation that the concentration of estradiol is less than 50pg/ml.
Sponsors
Suzuki Nao
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1, Diagnosed as Breast cancer with cytological or histological study 2, There is consult by letter from medical doctor who follow up the patient 3, Age 18 to 45 years-old 4, Expectable long-survival case 5, Written informed consent
Exclusion criteria
Exclusion criteria: 1, After bilateral ovariectomy 2, The patients have past-history of ovarian cancer or cervical cancer(adenocarcinoma). If there are possibilities to get worse do to fertility treatment. 3, Pregnant women 4, During lactation 5, There are severe complications (e.g. uncontrollable DM, Auto immune disease which cause thrombosis easily, past history of thrombosis) 6, AST or ALT > 100U 7, BUN > 25mg/dl, or Cre > 2.0 mg/dl 8, The patients who are determined as ineligible cases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of recurrence, Birth abnormality. | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of extracted oocyte, fertilization rate, birth rate. | — |
Contacts
Public ContactSeido Takae
St. Marianna University School of Medicine
Outcome results
None listed