Efficiency of V.D or V.E on osteoarthritis

Clinical effect of vitamin D or vitamin E therapy on osteoarthritis of the knee joint - effect of V.D or V.E therapy on OA

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs031180357

Enrollment

Registered

2019-03-18

Start date

2018-06-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the knee joints osteoarthritis, knee joint

Interventions

Taking intervention and control drugs on sale

vitamin

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Volunteer in medial knee osteoarthritis with Kellgren-Lawrence classification stage 2-4

Exclusion criteria

Exclusion criteria: Volunteer with including severe renal disorder,with talking parathyroid hormone, magnesium,supplements and osteoporosis

Design outcomes

Primary

Measure	Time frame
Questionnaires on subjective symptoms (Health-related QOL SF-36, Japanese Orthopedic Surgery Association, Functional Assessment Scale for Osteoarthritis Patients (JKOM), Motor Function (Grip strength, Quadriceps muscle strength, Performance test:(Timed-Single-Leg-Standing test, 10 meter walking test)	—

Secondary

Measure	Time frame
Presence or absence of side effects due to long term oral administration:Liver function (AST, ALT,rGTP), Renal function(BUN, Cr),Ca,P,ALP,UA Serum levels of hs-CRP,25(OH)VD,TGF-beta,Ca. Whole body DEXA (Bone density, muscle mass) X-ray (standing AP and MTP view) and MRI of knee joint	—

Contacts

Public ContactHiroaki Kanazawa

Juntendo Tokyo Koto Geriatric Medial Center

h-kanazawa@juntendo.ac.jp+81-356323111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026