diseases in the uterine cavity(ex: uterine myoma, endometrial polyp, uterine corpus cancer, endometr diseases in the uterine cavity, uterine myoma, endometrial polyp, endometrial cancer, endometrial hyperplasia
Conditions
Interventions
Patients are given aminolevrin acid 20mg/kg about four hours before hysteroscopic operation once.
They are performed hysteroscopic photodynamic diagnosis during operation.
D015907, D000284
Sponsors
Banno Kouji
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Patients who have diseases in uterine cavity. Patients who plan to undergo hysteroscopic operation for those diseases at the department of obstetrics and gynecology of Keio university hospital.
Exclusion criteria
Exclusion criteria: 1. under 20 years old 2. BMI>30 3. the medical history of endometrial entirely curettage in recent 14 day2. 4. the allergic history for the analog of the porphyrin. 5. porphyria 6. the medicine that is known for the cause of photosensitivity (ex. tetracycline antibacterial agent, medicine of sulfonamide, new quinolone antibacterial agent, hypericin and St.John's Wort. 7. the possibility of pregnant or blest feeding. 8. the diabetes mellitus and/or hyperlipidemia which is not controlled. 9. other endocrine diseases which are not controlled. 10. considered inadequate for this trial by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diagnostic accuracy for the malignant disease. | — |
Secondary
| Measure | Time frame |
|---|---|
| relationship between pathological findings and strength of the fluorescence adverse events (based on CTCAE v4.0-JCOG) | — |
Contacts
Public ContactKouji Banno
Keio University School of Medicine
Outcome results
None listed