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Clinical [F18]SNFT-1 PET Research

Clinical evaluation on usefulness and safety of a new Tau-specific PET probe [F18]SNFT-1 - Clinical evaluation of [F18]SNFT-1 PET

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs021260016
Enrollment
10
Registered
2026-06-09
Start date
2026-07-02
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer-type dementia Alzheimer-type dementia

Interventions

1) Intravenous administration of [18F]SNFT-1 2) PET/CT imaging

Sponsors

Kaneta Tomohiro
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Healthy volunteers and patients with Alzheimer-type dementia. will be selected based on the following exclusion criteria: 1. Individuals aged 18 years or older at the time of consent acquisition. 2. Individuals for whom written consent has been obtained from the subject (or, in the case of patients, from the subject and their authorized representative).

Exclusion criteria

Exclusion criteria: Subjects shall be excluded from the study if they are considered undesirable for the following reasons: 1) Individuals with organic brain disorders (including a history of definite cerebral infarction, Parkinson's disease, or related disorders). 2) Individuals with substance-related disorders (e.g., drug dependence). 3) Individuals with complications from serious diseases, or those with such a history whom the physician serving as the principal investigator deems unsuitable for this study. 4) Pregnant individuals, those who may be pregnant, and breastfeeding individuals. 5) Individuals weighing 80 kg or more. 6) Individuals with alcohol hypersensitivity. 7) Individuals whose living or working environment exposes them to radiation exceeding 10 mSv per year. 8) Students of division of Diagnostic Image Analysis of Tohoku University. 9) Other individuals deemed unsuitable as subjects by the physician serving as the researcher.

Design outcomes

Primary

MeasureTime frame
Radioation Dose (only for healthy volunteers)

Secondary

MeasureTime frame
1. Brain Imaging Evaluation 2. Safety Evaluation of PET Tracer

Contacts

Public ContactTomohiro Kaneta

Tohoku University

tomohiro.kaneta.d5@tohoku.ac.jp+81-22-717-7872

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026