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Lactobacillus oral care and the incident rate of Pneumonia after esophagectomy for Esophageal Cancer patients.

Improvement of oral environment with toothpaste and mouse wash containing Lactobacillus and the incident rate of pneumonia after esophagectomy for esophageal cancer patients. - LacPEC study

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTs021230010
Enrollment
60
Registered
2023-06-16
Start date
2023-06-16
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia and anastomotig leakage after esophagectomy for eophageal cancer patients pneumonia anastomotic leakage esophagectomy complication oral

Interventions

Improvement of oral environment with toothpaste and mouse wash containing Lactobacillus
The practice of personal hygiene of the mouth.
Lactobacillus oral care

Sponsors

Sato Yusuke
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patient who were pathologically diagnosed with Esophageal cancer, including Squamous cell carcinoma, adenocarcinoma, malignant melanoma, and other histological types. 2) Patient who and whose family selected esophagectomy with reconstruction as treatment. 3) Patient who were approved for esophagectomy even with other cancer. 4) Patient over 20 and under 85 years old at agreement. 5) Patient who agreed with written consent based on his free-will after a sufficient explanation.

Exclusion criteria

Exclusion criteria: 1) Patient who were not approved for esophagectomy before esophagectomy, or who and whose family declined esophagectomy. 2) Patient who needed period of suspension (more than 1 week) of interventional drug. 3) Patient who were not appropriate for inclusion.

Design outcomes

Primary

MeasureTime frame
The incident rate of pneumonia more than Clavien-Dindo II

Secondary

MeasureTime frame
The incident rate of anastomotic leakage more than Clavien-Dindo I

Contacts

Public ContactYusuke Sato

Akita University Hospital

yusuke@doc.med.akita-u.ac.jp+81-18-884-6132

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026