Healthy adults
Conditions
Interventions
Six broccoli-based supplements or placebo capsules per days will be taken for 14 days.
Sponsors
Itoh Ken
Natural Wellness Research Department, Innovation Division, KAGOME, CO., LTD.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Subjects who satisfies all follwing criteria. 1.Healthy adults aged >= 20 years to =< 35 years at the start of the trial. 2.Who can make self-judgment, voluntarily agree to participate to this trial, and provide written informed consent. 3.Those who are judged to have high SFN absorption efficiency in a preliminary study of 20-40 people.
Exclusion criteria
Exclusion criteria: 1. Subjects who have food allergy to the test supplements 2. Subjects who are pregnant, will hope pregnancy, or breast-feed during the study period 3. Subjects who suffer from psychiatric disease or express psychiatric symptoms 4. Subjects who join other clinical trials 5. Subjects who are judged unsuitable for this trial by the principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Antioxidant capacity of plasma (GSH, GSSH, GSH polysulfides, GSSG, Oxidized GSH polysulfides, GSH/GSSG, Cysteine (Cys), CysSSH, Cys polysulfides, Cystine, Oxidized Cys polysulfides, Cys/Cystine, Homocysteine, Homocysteine persulfide, Bis-S-HPE-AM, Bis-SS-HPE-AM, BAP) 2. Blood metabolites | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.SFN absorption efficiency 2.Biochemical test (AST, ALT, T-Bil, gamma-GTP) 3.Relationship between SFN absorption efficiency and antioxidative level in plasma 4.Relationship between SFN absorption efficiency and metabolites in plasma | — |
Contacts
Public ContactKen Itoh
Hirosaki University Graduate School of Medicine
Outcome results
None listed