early gastric cancer
Conditions
Interventions
L-menthol is directly endoscopically applied to early gastric cancer.
Sponsors
Hikichi Takuto
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients who provide written informed consent to participate in the research. 2) Men and women who are 20 years of age or older when consent is obtained. 3) Patients are histologically diagnosed as a gastric cancer. 4) EGC lesion has any of the following. (1) Macroscopic intramucosal cancer (cTIa) of 3 cm or less, differentiated cancer without ulceration (UL0) (2) Macroscopic intramucosal cancer (cTIa) of 3 cm or less, differentiated cancer, with ulceration (UL1) (3) Macroscopic intramucosal cancer (cTIa) of 2 cm or less, undifferentiated cancer without ulceration (UL0).
Exclusion criteria
Exclusion criteria: 1) A lesion that does not fit in one visual field of an endoscopic image. 2) Lesions on the cardia or pylorus. 3) Easy bleeding lesion. 4) Patients with a history of hypersensitivity to l-menthol. 5) Patients who have been judged by the main reseacher to be inappropriate for inclusion in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of lesions where the color difference between EGC and surrounding mucosa in LCI is 5 or more. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Proportion of lesions with a color difference of 5 or more between EGC and surrounding mucosa in WLI and BLI. 2) Median color difference between EGC and surrounding mucosa (LCI, WLI, BLI) 3) Proportion of lesions with increased color difference after l-menthol spraying (LCI, WLI, BLI). 4) Proportion of lesions in which the lesions became easy to see after l-menthol spraying in the subjective judgment of the doctor (scoring). | — |
Contacts
Public ContactTsunetaka Kato
Fukushima Medical University Hospital
Outcome results
None listed