Evaluation of perflubutane with ultrasound-guided nerve block

Evaluation of perflubutane-enhanced ultrasonography agent "sonazoid" for the detection of the distribution pf local anesthesia after ultrasound-guided nerve block

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs021200011

Enrollment

Registered

2020-07-27

Start date

2020-09-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing nerve block during surgery and at pain clinic

Interventions

To evaluate whether perflubutane-enhanced ultrasonography can detect the distribution of local anesthetics injected by ultrasound-guided nerve block

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients needed nerve block (2) American Society of Anesthesiologists (ASA) classification1-3 (3) Over the age of 20 (4) Make and Female

Exclusion criteria

Exclusion criteria: (1) Patients having a pain, neuropathic pain, or paralysis at the site of nerve block (2) Egg allergy, or contrast medium allergy (3) histry of anaphylaxy shock (4) Patients with arteriovenous shunt in cardia and lung (5) Severe heart disease (6) Severe pulmonary disease (7) Patients with pregnacy or nursing (8) Emergency surgery (9) Patients considered ineligible for this study

Design outcomes

Primary

Measure	Time frame
Evaluation of efficacy of perflubutane for the detection of local anesthetics distribution in nerve block and comparison with radiographic contrast media	—

Secondary

Measure	Time frame
Investigation of adverse event caused by perflubutane injection within 24 hours after injection of it	—

Contacts

Public ContactEiko Onishi

Tohoku University Hospital

e-onishi@med.tohoku.ac.jp+81-22-717-7321

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026