Squamous cell carcinoma of vulva
Conditions
Interventions
RT was performed according to the RT guidelines of the Japanese Society for Radiation Oncology
JASTRO. The target margins were consisted as follows: clinical target volume
CTV was gross tumor volume
GTV plus 2 cm margin in all directions
planning target volume
PTV was CTV plus 0.5 cm margin in all directions. A leaf margin was also taken 0.5 cm around the PTV. For cases with inguinal lymph node metastasis, the radiation field was expanded to the whole pelvi
1.2 to 2.0 Gy per fraction, 5 days a week. RT consisted of external beam radiation using AP PA opposed beams generated by a linear acceler- ator with 6 to 18 MV X ray. Electrons were used for boosting
Sponsors
Futagami Masayuki
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Patients with a histiological diagnosis of squamous cell carcinoma of vulva 2) Patients with measurable or evaluable lesions 3) First treatment case 4) Age is from 20 to 79 years old 5) ECOG Performance Status is 0-2 6) Major organ function is maintained 7) Patients who signed informed consent
Exclusion criteria
Exclusion criteria: 1) Patients who have received prior chemotherapy or/and irradiation therapy 2) Patients with active synchronous cancer 3) Patients with active infection 4) Patients with severe complication, bronchial asthma, interstitial pneumonia, ischemic heart disease, diabetic mellitus and arrhythmia 5) Patients with massive pleural effusion or asites 6) Patients with history of hypersensitivity reaction 7) Patients with pregnant or lactating 8) Patients who is difficult to treat and follow in this study 9) Patients who are not eligible in this study by study chair or study co-chair.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response of tumor | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression free survival, Overall survival | — |
Contacts
Public ContactMasayuki Fuatgami
Hirosaki University Hospital
Outcome results
None listed