Contrast-enhanced ultrasonic diagnosis of head and neck tumor

Diagnostic image of the head and neck tumor by ultrasonography using micro-bubble contrast medium -Phase I study of the efficacy of sonazoid targeting head and neck tumors-

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs021180035

Enrollment

100

Registered

2019-03-25

Start date

2015-07-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck tumor

Interventions

intra-venous injection of contrast-medium

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. patients with untreated head and neck tumor 2. patients with the tumor which will be resected and diagnosed by histopathological examination 3. patients more than 20 years old

Exclusion criteria

Exclusion criteria: 1. patients with allergy to egg or ingredient made from egg 2. patients with arterio-venous shunt in heart or lung 3. patients with severe heart disease 4. patients with severe lung disease 5. patients who will undergo laparoscopic examination or digestive tract examination using effervescent agent on the same day undergoing this examination 6. pregnant or possible pregnant patients and breast-feeding patients 7. patients who can not receive contrast-enhanced MRI or CT examination 8. patients whose target tumors are recurrent diseases 9. patients who received or will be received contrast-enhanced media (Iode media, MRI media, other contrast-enhanced media for ultrasonography etc.) during the day before and after the day of sonazoid injection 10. patients who responsible doctors recognize inappropriate for this study

Design outcomes

Primary

Measure	Time frame
Differential diagnosis of benign and malignant tumor	—

Countries

Japan, many

Contacts

Public ContactKiyoto Shiga

Iwate Medical University

kshiga@iwate-med.ac.jp+81-19-613-7111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026