Beneficial effects of trehalose eye-drops on the postoperative course after anti-glaucomatous trabeculectomy surgery

Effect of trehalose eye-drops on the maintenance of filtration bleb after trabeculectomy - postoperative instillation of trehalose after trabeculectomy

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs021180008

Enrollment

Registered

2019-03-15

Start date

2019-06-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary or secondary open angle glaucoma glaucoma, open angle

Interventions

topical instillation of 0.5% trehalose or saline in addition to regular medication for a month after trabeculectomy

D009883

trehalose eye-drops

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with primary or secondary open angle glaucoma

Exclusion criteria

Exclusion criteria: patients with angle closure galaucoma, eyes with previous history of trabeculectomy

Design outcomes

Primary

Measure	Time frame
quantitive analyses of anterior segment OCT findings of morphology of filtration bleb after trabeculectomy	—

Secondary

Measure	Time frame
intraocular pressure	—

Contacts

Public ContactMitsuru Nakazawa

Hirosaki University

mitsuru@hirosaki-u.ac.jp+81-172395094

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026