Examination of aroma inhalation effect on post oral surgery nausea

Examination of Aroma Essencial Oil Inhalation Effect on Post Oral Surgery Nausea Severity: Single-Blind Randomized Controlled Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs011210021

Enrollment

182

Registered

2021-07-16

Start date

2021-08-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea

Interventions

Inhale aroma essential oils (blends) of lavender, ginger and peppermint diluted to 1% at the time of postoperative nausea. The inhalation time is 2 minutes, followed by another 2 minutes of inhalation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients scheduled to undergo oral surgery under general anesthesia at Surgical Center or Center for Oral Surgery of Hokkaido University Hospital 2. Age 20+ 3. ASA physical status class 1 or 2 4. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Lack of judgment, such as intellectual disability 2. Allergy to the aroma essential oil 3. Olfactory disorder 4. Hemorrhagic diathesis 5. ICU management after general anesthesia 6. Scheduled to administer intraoperative antiemetic prophylaxis 7. Judged by the primary sponser to be inappropriate as research subjects

Design outcomes

Primary

Measure	Time frame
Amount of change in the severity of nausea with and without aroma essential oil at the time of postoperative nausea.	—

Secondary

Measure	Time frame
Antiemetics use rate, drug name and dose used, patient satisfaction, adverse events.	—

Contacts

Public ContactEmi Ishikawa

Hokkaido University Hospital

esmuin128@den.hokudai.ac.jp+81-11-706-4336

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026