PPOAFVALVEtrial

Prophylaxis of postoperative atrial fibrillation by L-Carnitine in heart valve surgery - a randomized controlled trial - PPOAFVALVEtrial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTs011190012

Enrollment

145

Registered

2020-03-18

Start date

2020-05-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart valve disease Heart valve disease

Interventions

Medication (L-Carnitine 30ml/3X for 7 days)

D065129

Prevention of postoperative atrial fibrillation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who undergo heart valve surgery

Exclusion criteria

Exclusion criteria: Patients with atrial fibrillation ventricular arrhythmia, unstable angina, acute myocardial infarction, hemodialysis, digitalis, and class I and III antiarrhythmic agents; pregnant women; emergent case

Design outcomes

Primary

Measure	Time frame
Postoperative atrial fibrillation for more than 30 seconds within 5 days after surgery	—

Secondary

Measure	Time frame
Duration of postoperative hospitalization; complications; duration of atrial fibrillation; postoperative atrial flutter for more than 30 seconds within 5 days after surgery; duration of atrial flutter	—

Contacts

Public ContactYasushige Shingu

Hokkaido University Hospital

shingu@huhp.hokudai.ac.jp+81-11-706-6042

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026