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Bone marrow transplantation for osteonecrosis

Efficacy study of autologous concentrated bone marrow transplantation for idiopathic osteonecrosis of the femoral head. - ACBM for IONF

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-jRCTc032200229
Enrollment
34
Registered
2020-12-04
Start date
2023-01-12
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic Osteonecros is of Femoral Head

Interventions

Sponsors

Watari Taiji
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) bilateral idiopathic femoral head necrosis 2) One side was crshed(stage 3A or higher), and total hip arthroplasty is performed 3) Other side was idiopathic osteonecrosis of femoral head; Stage 1 or 2 and type C 4) Age 20 years old and more than 20 years old, 50 years old and less than 50 years old

Exclusion criteria

Exclusion criteria: 1) Patients with abnormal platelet counts inperipheral blood (less than 50,000 / uL) or patients with obvious bleeding tendency 2) Patient who smokes a lot (Brinkman index > 600) 3) Anemia less than Hb10 4) Uncontrolled blood gloucose 5) Patients with malignancy 6) Patients less than 6 months after onset of cardiac inf arction or cerebral infarction 7) Predictive survival period is less than 1 year 8) Active infectious disease (HBV, HCV, HIV, syphilis) 9) Dialysis patients 10) Patiens with dementia or coma 11) Previous surgical history for proximal femur 12) Anesthesist has determined that it is not suitable for general anesthesia 13) Doctor has determined that it is not suitable for this clinical study

Design outcomes

Primary

MeasureTime frame
Ratio of collapsed femoral head.

Secondary

MeasureTime frame
- Adverse event - Pain - Hip Function - Necrotic volume

Countries

Japan

Contacts

Public ContactKeiko Wakana

Juntendo Hospital,Juntendo university school of medicine

kwakana@juntendo.ac.jp+81-3-3814-5672

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026