Bone marrow transplantation for osteonecrosis

Autologous concentrated bone marrow transplantation for idiopathic osteonecrosis of femoral head. - ACBM for IONF

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCTc032200027

Enrollment

Registered

2020-05-07

Start date

2020-05-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic Osteonecrosis of Femoral Head

Interventions

Administration of cell processing products .

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Idiopathic osteonecrosis of femoral head; Stage 1,2, and 3A 2) Age more than 20 years old

Exclusion criteria

Exclusion criteria: 1) Patients with abnormal platelet counts in peripheral blood 2) Patient who smoke s a lot (Brinkman index > 600) 3) Treatment with anticoagulants (except for Bi aspirine) 4) Uncontrolled diabetes mellitus:HbA1c not lower than 9.0% according to latest laboratory data obtained within 14 days before registration 5) Patients with malignancy 6) Patients less than 6 months after onset of cardiac infarction or cerebral infarction 7) Predictive survival period is les s than 1 year 8) Active infectious disease (HBV, HCV, HIV, syphilis) 9) Dialysis patients 10) Less than 20 years old 11) Patiens with dementia or coma 12) Previous surgical history for proximal femur 13) Anesthesist has determined that it is not suitable for general anesthesia 14) Doctor has determined that it is not suitable for this clinical study

Design outcomes

Primary

Measure	Time frame
Safety	—

Secondary

Measure	Time frame
- Pain - Hip Function - Changement of staging - Necrotic volume	—

Countries

Japan

Contacts

Public ContactMasubuchi Yosuke

Juntendo University

y-masubuchi@juntendo.ac.jp+81-3-3814-5672

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026